Population pharmacokinetic modeling of paired plasma-breast milk lamivudine data for estimation of infant exposure in breastfeeding mother-infant pairs

• Prif Awduron: Francis Williams Ojara (Awdur), Aida N. Kawuma (Awdur), Shadia Nakalema (Awdur), Isabella Kyohairwe (Awdur), Ritah Nakijoba (Awdur), Mohammed Lamorde (Awdur), Henry Pertinez (Awdur), Saye Khoo (Awdur), Catriona Waitt (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Wiley, 2024-11-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Abstract Around 1.2 million women living with HIV give birth annually, majority of whom will breastfeed their infants while receiving antiretroviral therapy (ART). Lamivudine, a component of first‐line ART regimens crosses from maternal plasma to breast milk, with measurable concentrations in some b...