Population pharmacokinetic modeling of paired plasma-breast milk lamivudine data for estimation of infant exposure in breastfeeding mother-infant pairs

• Auteurs principaux: Francis Williams Ojara (Auteur), Aida N. Kawuma (Auteur), Shadia Nakalema (Auteur), Isabella Kyohairwe (Auteur), Ritah Nakijoba (Auteur), Mohammed Lamorde (Auteur), Henry Pertinez (Auteur), Saye Khoo (Auteur), Catriona Waitt (Auteur)
• Format: Livre
• Publié: Wiley, 2024-11-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Abstract Around 1.2 million women living with HIV give birth annually, majority of whom will breastfeed their infants while receiving antiretroviral therapy (ART). Lamivudine, a component of first‐line ART regimens crosses from maternal plasma to breast milk, with measurable concentrations in some b...