Population pharmacokinetic modeling of paired plasma-breast milk lamivudine data for estimation of infant exposure in breastfeeding mother-infant pairs

• Үндсэн зохиолчид: Francis Williams Ojara (Зохиогч), Aida N. Kawuma (Зохиогч), Shadia Nakalema (Зохиогч), Isabella Kyohairwe (Зохиогч), Ritah Nakijoba (Зохиогч), Mohammed Lamorde (Зохиогч), Henry Pertinez (Зохиогч), Saye Khoo (Зохиогч), Catriona Waitt (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Wiley, 2024-11-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Abstract Around 1.2 million women living with HIV give birth annually, majority of whom will breastfeed their infants while receiving antiretroviral therapy (ART). Lamivudine, a component of first‐line ART regimens crosses from maternal plasma to breast milk, with measurable concentrations in some b...