Population pharmacokinetic modeling of paired plasma-breast milk lamivudine data for estimation of infant exposure in breastfeeding mother-infant pairs

• Principais autores: Francis Williams Ojara (Autor), Aida N. Kawuma (Autor), Shadia Nakalema (Autor), Isabella Kyohairwe (Autor), Ritah Nakijoba (Autor), Mohammed Lamorde (Autor), Henry Pertinez (Autor), Saye Khoo (Autor), Catriona Waitt (Autor)
• Formato: Livro
• Publicado em: Wiley, 2024-11-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Around 1.2 million women living with HIV give birth annually, majority of whom will breastfeed their infants while receiving antiretroviral therapy (ART). Lamivudine, a component of first‐line ART regimens crosses from maternal plasma to breast milk, with measurable concentrations in some b...