Characterization of Lemongrass Extract (Cymbopagon citratus) Nanoemulsion and Its Application as an Antibiofilm Agent in Acrylic Resin

• Main Authors: Vinna K. Sugiaman (Author), Rosalina I. Saputri (Author), Silvia Naliani (Author), Jane A. V. Wibisono (Author), Jeffrey (Author), Wayan L. Demolsky (Author), Wahyu Widowati (Author), Agung Novianto (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 0976-4879; 0975-7406; 10.4103/jpbs.jpbs_418_24
• Keywords: acrylic resin; antibiofilm; candida albicans; cymbopogon citratus; nanoemulsion; streptococcus mutans; Pharmacy and materia medica; RS1-441; Analytical chemistry; QD71-142
• Source: Journal of Pharmacy and Bioallied Sciences, Vol 16, Iss Suppl 3, Pp S2715-S2717 (2024)

Background: An antimicrobial agent is needed for denture cleaning, such as lemongrass (LG), which has a bioactive antimicrobial component. Methods: This research analyzed LG extract nanoparticles with a particle size analyzer, ZPA, and biofilm formation inhibition on resin acrylic surfaces. Results: We found that there is high stability in nanoparticle size, while other concentrations, including chlorhexidine as a positive control, did not show any statistical differences. Conclusion: Lemongrass oil nanoemulsion has proved to be an antibiofilm and effective as a denture cleaning agent because of its ability to inhibit Streptococcus mutans and Candida albicans growth.