Relative children's lipid accumulation with hypertension in Chinese children and adolescents

• Main Authors: Zizhe Zhang (Author), Li Zhang (Author), Lili Sun (Author), Bangxuan Wang (Author), Yongting Yuan (Author), Huaiquan Gao (Author), Lianguo Fu (Author)
• Format: Book
• Published: BMC, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 10.1186/s12889-021-11868-5; 1471-2458
• Keywords: Hypertension; children's lipid accumulation product; Children and adolescents; Public aspects of medicine; RA1-1270
• Source: BMC Public Health, Vol 21, Iss 1, Pp 1-8 (2021)

Abstract Background This study aimed to develop a novel indicator associated with hypertension in Chinese children and adolescents, the relative children's lipid accumulation product (RCLAP). Methods A cross-sectional study was conducted in 2018. A total of 683 students aged 8-15 years were recruited via a stratified cluster sampling Methods. Anthropometric indexes (waist circumference (WC), Body mass index (BMI), Waist-height ratio (WHtR), logarithm children LAP (LnCLAP), RCLAP per height (RCLAP-H)) were standardized using a z-score method (standardized variables: SWC, SBMI, SWHtR, SLnCLAP, SRCLAP-H). A logistic regression model was performed to evaluate the association of the above indicators with the outcome of hypertension. Results The overall prevalence of hypertension was 5.7% (5.5% in boys, 6.0% in girls). SWC ≥ P 75, SBMI ≥ P 75, SWHtR ≥ P 75, SlnCLAP ≥ P 75 and SRCLAP-H ≥ P 75 significantly increased risk of hypertension, with odds ratios (OR) of 2.21 (95% confidence interval (CI): 1.13, 4.30), 2.30 (1.18, 4.49), 2.64 (1.35, 5.14), 4.43 (2.28, 8.61), and 4.49 (2.31, 8.71), respectively. Conclusion RCLAP is a novel indicator associated with hypertension in Chinese children and adolescents, and it performs better than WC, BMI, WHtR and children LAP.