Reassessing therapeutic antibodies for neglected and tropical diseases.

• Hauptverfasser: Rob Hooft van Huijsduijnen (Verfasst von), Somei Kojima (Verfasst von), Dee Carter (Verfasst von), Hisafumi Okabe (Verfasst von), Akihide Sato (Verfasst von), Wataru Akahata (Verfasst von), Timothy N C Wells (Verfasst von), Kei Katsuno (Verfasst von)
• Format: Buch
• Veröffentlicht: Public Library of Science (PLoS), 2020-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

In the past two decades there has been a significant expansion in the number of new therapeutic monoclonal antibodies (mAbs) that are approved by regulators. The discovery of these new medicines has been driven primarily by new approaches in inflammatory diseases and oncology, especially in immuno-o...