CD82 attenuates TGF-β1-mediated epithelial-mesenchymal transition by blocking smad-dependent signaling in ARPE-19 cells

• Main Authors: Hyesook Lee (Author), Jung-Hwa Han (Author), Yun Jeong Kang (Author), Hyun Hwangbo (Author), Aeseon Yoon (Author), Hyung-Sik Kim (Author), Dongjun Lee (Author), Soo Yong Lee (Author), Byung Hyun Choi (Author), Jae-Joon Kim (Author), Seo Rin Kim (Author), Yung Hyun Choi (Author), Jin Hur (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In retinal pigment epithelial (RPE) cells, transforming growth factor-beta (TGF-β) plays a critical role in epithelial-mesenchymal transition (EMT), which contributes to various fibrotic retinal disorders. In the present study, we investigated the effect of recombinant human cluster of differentiati...