Impact of cancer mutational signatures on transcription factor motifs in the human genome
Abstract Background Somatic mutations in cancer genomes occur through a variety of molecular mechanisms, which contribute to different mutational patterns. To summarize these, mutational signatures have been defined using a large number of cancer genomes, and related to distinct mutagenic processes....
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Main Authors: | Calvin Wing Yiu Chan (Author), Zuguang Gu (Author), Matthias Bieg (Author), Roland Eils (Author), Carl Herrmann (Author) |
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Format: | Book |
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BMC,
2019-05-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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