Trend Analysis of Lung Cancer Incidence and Mortality in Xiamen (2011-2020)

• Main Authors: Cong J (Author), Chi J (Author), Zeng J (Author), Lin Y (Author)
• Format: Book
• Published: Dove Medical Press, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 1179-1594
• Keywords: lung cancer; incidence; mortality; trend; survival analyze; Public aspects of medicine; RA1-1270
• Source: Risk Management and Healthcare Policy, Vol Volume 17, Pp 2375-2384 (2024)

Jianni Cong,1,&ast; Jiahuang Chi,2,&ast; Junli Zeng,3 Yilan Lin2 1School of Health Management, Binzhou Medical University, Shandong, People's Republic of China; 2Department of Chronic and Non-Communicable Diseases Control and Prevention, Xiamen Center for Disease Control and Prevention, Xiamen, People's Republic of China; 3Department of Respiratory Center, The Second Affiliated Hospital of Xiamen Medical College, Xiamen, People's Republic of China&ast;These authors contributed equally to this workCorrespondence: Yilan Lin, Email [e-mail]: To analyze the trends of lung cancer incidence and mortality in Xiamen from 2011 to 2020 and provide some clues for the lung cancer prevention and control.Methods: The data was obtained from the Xiamen City Cancer Register in Fujian Province, China. The data was updated on Sep 30, 2023. The codes of C33-C34 were used to identify the lung cancer. The newly diagnosed lung cancer patients during the period of 2011- 2020 in Xiamen City were included in the evaluation of incidence and mortality and Cox analysis.Results: A total of 11408 lung cancer patients were enrolled. The crude incidence rate was 52.78 per 100000 and the age-standardized incidence rate (ASIWR) was 40.67 per 100000 from 2011 to 2020. Both the crude incidence rate of lung cancer (AAPC =5.92, P value < 0.001) and ASIWR (AAPC = 4.93, P value < 0.001) showed increasing trends. The crude incidence rate in female increased 4.90 times faster as that in male (AAPC: 12.34/2.52). The crude mortality rate and the age-standardized mortality rate (ASMWR) were 37.25 per 100000 and 28.30 per100000. The 5-year age-standardized relative survival rate (ARS) was 18.62% (95% CI: 17.63- 19.67%). The 5-year ARS was higher in women than men (26.35% vs 15.28%) and higher in urban than rural areas (21.44% vs 11.96%). Patients with lower education levels had significantly lower ARS than those with higher education (14.66% vs 31.53%). The 5-year ARS improved notably from 2016- 2020 compared to 2011- 2015 (22.23% vs 13.21%). Farmers had the lowest ARS among occupations [13.34% (95% CI:11.93- 14.92%)]. There were all increasing trends in 1-year, 3-year, 5-year, and 10-year ARS rates between 2011 and 2020 (all P values of AAPC< 0.05).Conclusion: Lung cancer incidence in Xiamen increased, while mortality decreased with improved survival. Developing more perfect need to consider the differences in the social environment and other factors.Keywords: lung cancer, incidence, mortality, trend, survival analyze