Report of 2 Novel Presentations of Subcutaneous Fat Necrosis of the Newborn

Subcutaneous fat necrosis of the newborn (SCFNN) is a rare form of panniculitis classically affecting healthy full-term infants. There are a number of predisposing factors including perinatal asphyxia. The condition generally has a benign course with spontaneous resolution, but monitoring for metabo...

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Bibliographic Details
Main Authors: Susanna M.H. Kannenberg (Author), H. Francois Jordaan (Author), Willem I. Visser (Author), Fatima Ahmed (Author), A. Fourie Bezuidenhout (Author)
Format: Book
Published: MDPI AG, 2019-06-01T00:00:00Z.
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Summary:Subcutaneous fat necrosis of the newborn (SCFNN) is a rare form of panniculitis classically affecting healthy full-term infants. There are a number of predisposing factors including perinatal asphyxia. The condition generally has a benign course with spontaneous resolution, but monitoring for metabolic complications, in particular the potentially life-threatening complication of hypercalcaemia, is critical. The authors report 2 cases of preterm infants with perinatal asphyxia with atypical presentations of SCFNN: the first with bony involvement resembling Langerhans cell histiocytosis and with follicular pseudocarcinomatous hyperplasia on histology; and the second presenting with a huge haematoma requiring surgical debridement. Both cases were initially erroneously diagnosed as pyogenic infections.
Item Description:2296-3529
10.1159/000497176