Modeling of p-aminophenol compounds as analgesic antiinflammatory based on biologic activity and structure relationship

This research aim was to find out the new compounds model of paminophenol derivates which have analgesic anti-inflammatory activity based on structure and biologic activity relationship analysis by computation methods. Seventeen compounds of p-aminophenol derivates were used in this research, and si...

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Bibliographic Details
Main Authors: Pudjono (Author), Sri Sutji Susilowati (Author), Rehana (Author)
Format: Book
Published: Universitas Gadjah Mada, 2011-04-01T00:00:00Z.
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Summary:This research aim was to find out the new compounds model of paminophenol derivates which have analgesic anti-inflammatory activity based on structure and biologic activity relationship analysis by computation methods. Seventeen compounds of p-aminophenol derivates were used in this research, and six compounds known its analgesic-antiinflammatory activity were used for determine QSAR equation model. This research's result was a QSAR equation that can be using for synthesis the higher activity new compound of paminophenol. Key words : p-aminophenol compounds, analgesic anti-inflammatory activity, structure and activity relationship, QSAR equation, computation methods
Item Description:http://dx.doi.org/10.14499/indonesianjpharm0iss0pp144-150
2338-9427
2338-9486