The expression of Bcl-2 in oral squamous cell carcinoma-A review

Currently, oral cancer is one of the most alarming health problems facing mankind. More than 90% of all oral cancers are oral squamous cell carcinoma (OSCC). BCL-2 proteins are one of the most prominent anti-apoptotic proteins expressed in OSCC. They contribute to cancer development and mediate resi...

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Bibliographic Details
Main Authors: Jayakumar Arumugam (Author), Nadeem Jeddy (Author), Ananthalakshmi Ramamurthy (Author), Radhika Thangavelu (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2017-01-01T00:00:00Z.
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Summary:Currently, oral cancer is one of the most alarming health problems facing mankind. More than 90% of all oral cancers are oral squamous cell carcinoma (OSCC). BCL-2 proteins are one of the most prominent anti-apoptotic proteins expressed in OSCC. They contribute to cancer development and mediate resistance to current anticancer treatments. Various studies have been conducted to evaluate the expression of Bcl-2 in OSCC. This article emphasizes the importance of Bcl-2 expression as a prognostic indicator in OSCC.
Item Description:0975-8844
10.4103/jofs.jofs_88_16