Hierarchical Porous Carbon-PLLA and PLGA Hybrid Nanoparticles for Intranasal Delivery of Galantamine for Alzheimer's Disease Therapy

• Main Authors: Stavroula G. Nanaki (Author), Konstantinos Spyrou (Author), Chryssa Bekiari (Author), Pelagia Veneti (Author), Turki N. Baroud (Author), Niki Karouta (Author), Ioannis Grivas (Author), Georgios C. Papadopoulos (Author), Dimitrios Gournis (Author), Dimitrios N. Bikiaris (Author)
• 格式: 图书
• 出版: MDPI AG, 2020-03-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

In the present study, poly(l-lactic acid) (PLLA) and poly(lactide-<i>co</i>-glycolide) (PLGA) hybrid nanoparticles were developed for intranasal delivery of galantamine, a drug used in severe to moderate cases of Alzheimer&#8217;s disease. Galantamine (GAL) was adsorbed first in hier...