Use of vitamin D and infection in patients with chronic kidney disease

• Main Authors: Emanuela Cardoso da Silva (Author), Mônica Taminato (Author), Cassiane Dezoti da Fonseca (Author), Graciana Maria de Moraes (Author), Maria Cristina Barbosa Longo (Author), Cibele Esmanhoto Grothe (Author), Angélica Gonçalves Silva Belasco (Author), Dulce Aparecida Barbosa (Author)
• Format: Book
• Published: Associação Brasileira de Enfermagem.
• Subjects: article
• Online Access: Connect to this object online.

Summary

ABSTRACT Objective: To evaluate the effectiveness of vitamin D supplementation as protection factor against infection of patients with chronic kidney disease on conservative treatment. Method: Retrospective cohort study carried out between 2013 and 2016 in the Conservative Treatment Outpatient Clinics (Ambulatório de Tratamento Conservador) of the Hypertension and Kidney Hospital (Hospital do Rim e Hipertensão) of the Universidade Federal de São Paulo. Data on sociodemographic factors, comorbidity, infection episodes and use or nonuse of vitamin D supplementation for at least 6 months were collected from medical records. The primary outcomes considered in both groups were: presence or absence of infection anywhere on the body (bloodstream, urinary, respiratory and surgical sites). Results: A total of 263 patients were included and those who received (n=43) vitamin D had 59% less chance of developing infections (OR=0.41; 95%CI; 0.15-0.99), when compared to those who did not receive. Conclusion: Vitamin D supplementation was a protective factor against infections of all causes.

Item Description

1984-0446
10.1590/0034-7167-2018-0640