Development and validation of a headspace gas chromatographic method for the determination of residual solvents in arterolane (RBx11160) maleate bulk drug

• Main Authors: Abhishek Gupta (Author), Yogendra Singh (Author), Kona S Srinivas (Author), Garima Jain (Author), V B Sreekumar (Author), Vinod Prasad Semwal (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective : Arterolane maleate is an antimalarial drug currently under Phase III clinical evaluation, and presents a simple, economical and scalable synthesis, and does not suffer from safety problems. Arterolane maleate is more active than artemisinin; and is cheap to produce. It has a longer lifet...