Relief Effects of Icariin on Inflammation-Induced Decrease of Tight Junctions in Intestinal Epithelial Cells

• Main Authors: Yanli Li (Author), Jie Liu (Author), Pawin Pongkorpsakol (Author), Zhengguo Xiong (Author), Li Li (Author), Xuemei Jiang (Author), Haixia Zhao (Author), Ding Yuan (Author), Changcheng Zhang (Author), Yuhui Guo (Author), Yaoyan Dun (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Inflammatory cytokines including TNF-α and IL-1β impair intestinal barrier function in aging by disrupting intestinal tight junction integrity. Icariin (ICA) has a variety of pharmacological effects. Indeed, ICA produces anti-inflammatory, anti-oxidative stress, and inhibitory effects on microRNA (m...