Cover Image

Phosphorylation of Beta-3 adrenergic receptor at serine 247 by ERK MAP kinase drives lipolysis in obese adipocytes

Objective: The inappropriate release of free fatty acids from obese adipose tissue stores has detrimental effects on metabolism, but key molecular mechanisms controlling FFA release from adipocytes remain undefined. Although obesity promotes systemic inflammation, we find activation of the inflammat...

Full description

Saved in:

Bibliographic Details
Main Authors:	Shangyu Hong (Author), Wei Song (Author), Peter-James H. Zushin (Author), Bingyang Liu (Author), Mark P. Jedrychowski (Author), Amir I. Mina (Author), Zhaoming Deng (Author), Dimitrije Cabarkapa (Author), Jessica A. Hall (Author), Colin J. Palmer (Author), Hassan Aliakbarian (Author), John Szpyt (Author), Steven P. Gygi (Author), Ali Tavakkoli (Author), Lydia Lynch (Author), Norbert Perrimon (Author), Alexander S. Banks (Author)
Format:	Book
Published:	Elsevier, 2018-06-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Sulfonylureas exert antidiabetic action on adipocytes by inhibition of PPARγ serine 273 phosphorylation
by: Bodo Haas, et al.
Published: (2024)

Genome-wide association study of adipocyte lipolysis in the GENetics of adipocyte lipolysis (GENiAL) cohort
by: Agné Kulyté, et al.
Published: (2020)

Adipose retinol saturase is regulated by β-adrenergic signaling and its deletion impairs lipolysis in adipocytes and acute cold tolerance in mice
by: Chen Li, et al.
Published: (2024)

Effect of physical exercise on lipolysis in white adipocytes
by: Junetsu Ogasawara, et al.
Published: (2012)

Ginsenoside Rb1 Induces Beta 3 Adrenergic Receptor-Dependent Lipolysis and Thermogenesis in 3T3-L1 Adipocytes and db/db Mice
by: Seona Lim, et al.
Published: (2019)

Corrigendum to "Genome-wide association study of adipocyte lipolysis in the GENetics of adipocyte lipolysis (GENiAL) cohort" [Molecular Metabolism 34 (2020) 85-96]
by: Agné Kulyté, et al.
Published: (2020)

Effect of Crocetin on Basal Lipolysis in 3T3-L1 Adipocytes
by: Francisco J. Cimas, et al.
Published: (2023)

Tumoral acidosis promotes adipose tissue depletion by fostering adipocyte lipolysis
by: Camille Lefevre, et al.
Published: (2024)

mTORC1 restrains adipocyte lipolysis to prevent systemic hyperlipidemia
by: Lauren M. Paolella, et al.
Published: (2020)

Extract of Paecilomyces hepiali mycelia induces lipolysis through PKA-mediated phosphorylation of hormone-sensitive lipase and ERK-mediated downregulation of perilipin in 3T3-L1 adipocytes
by: Mei Ge, et al.
Published: (2018)

Adipocyte-specific Beclin1 deletion impairs lipolysis and mitochondrial integrity in adipose tissue
by: Yeonho Son, et al.
Published: (2020)

Alisol A 24-acetate stimulates lipolysis in 3 T3-L1 adipocytes
by: Hai-xia Lou, et al.
Published: (2021)

Tbx15 is required for adipocyte browning induced by adrenergic signaling pathway
by: Wei Sun, et al.
Published: (2019)

cAMP driven UCP1 induction in human adipocytes requires ATGL-catalyzed lipolysis
by: Anand Desai, et al.
Published: (2024)

The effects of Bee Venom and Sweet Bee Venom to the preadipocyte proliferation and lipolysis of adipocyte, localized fat accumulation
by: Min-Ki Kim, et al.
Published: (2007)

Inhibition of the TNF-α-Induced Serine Phosphorylation of IRS-1 at 636/639 by AICAR
by: Tomohito Shibata, et al.
Published: (2013)

Vacuolar protein sorting 13C is a novel lipid droplet protein that inhibits lipolysis in brown adipocytes
by: Vanesa D. Ramseyer, et al.
Published: (2018)

The effect of quercetin on adipogenesis, lipolysis, and apoptosis in 3T3‐L1 adipocytes: The role of SIRT1 pathways
by: Mohammad Hasan Maleki, et al.
Published: (2024)

The neuropeptide TLQP-21 opposes obesity via C3aR1-mediated enhancement of adrenergic-induced lipolysis
by: Cheryl Cero, et al.
Published: (2017)

Phosphorylation of Hsp25 at serine 15 is promoted in immature fibers following in situ muscle contraction
by: Fuminori Kawano, et al.
Published: (2015)

Adiporedoxin, an upstream regulator of ER oxidative folding and protein secretion in adipocytes
by: Mark P. Jedrychowski, et al.
Published: (2015)

Erythroderma: analysis of 247 cases
by: Cidia Vasconcellos, et al.
Published: (1995)

Erythroderma: analysis of 247 cases
by: Cidia Vasconcellos, et al.
Published: (1995)

Erythroderma: analysis of 247 cases
by: Cidia Vasconcellos, et al.

Erythroderma: analysis of 247 cases
by: Vasconcellos Cidia, et al.
Published: (1995)

Adipocyte glucocorticoid receptor is important in lipolysis and insulin resistance due to exogenous steroids, but not insulin resistance caused by high fat feeding
by: Yachen Shen, et al.
Published: (2017)

Spinal cord NR1 serine phosphorylation and NR2B subunit suppression following peripheral inflammation
by: Del Valle-Pinero Arseima Y, et al.
Published: (2005)

Metformin Inhibits Expression and Secretion of PEDF in Adipocyte and Hepatocyte via Promoting AMPK Phosphorylation
by: Shumin Yang, et al.
Published: (2013)

Apparent histological changes of adipocytes after treatment with CL 316,243, a ß-3-adrenergic receptor agonist
by: Ghorbani M, et al.
Published: (2015)

Oleoylethanolamide enhances β-adrenergic-mediated thermogenesis and white-to-brown adipocyte phenotype in epididymal white adipose tissue in rat
by: Juan Suárez, et al.
Published: (2014)

Phosphorylation of islet-1 serine 269 by CDK1 increases its transcriptional activity and promotes cell proliferation in gastric cancer
by: Qiong Shi, et al.
Published: (2021)

Opipramol Inhibits Lipolysis in Human Adipocytes without Altering Glucose Uptake and Differently from Antipsychotic and Antidepressant Drugs with Adverse Effects on Body Weight Control
by: Christian Carpéné, et al.
Published: (2020)

Effects of Chowiseungcheng-tang Extracts on the Preadipocytes Proliferation in 3T3-L1 cell line, Lipolysis of Adipocytes in rat, and Localized Fat Accumulation by extraction methods
by: Jae-eun, Lee, et al.
Published: (2008)

Stat3 Tyrosine 705 and Serine 727 Phosphorylation Associate With Clinicopathological Characteristics and Distinct Tumor Cell Phenotypes in Triple-Negative Breast Cancer
by: Michaela Stenckova, et al.
Published: (2022)

The Cornhill Magazine (vol. XLII, no. 247 new series, January 1917)
by: Various

Endothelial NOX5 Expression Modulates Thermogenesis and Lipolysis in Mice Fed with a High-Fat Diet and 3T3-L1 Adipocytes through an Interleukin-6 Dependent Mechanism
by: Jorge G. García, et al.
Published: (2021)

Maria Nowacka, Etyka a transplantacje, PWN, Warszawa 2003, ss. 247
by: Jacek Meller
Published: (2004)

Cdkal1, a type 2 diabetes susceptibility gene, regulates mitochondrial function in adipose tissue
by: Colin J. Palmer, et al.
Published: (2017)

Beta-Adrenergic Agonists
by: Giovanni Barisione, et al.
Published: (2010)

Role of carboxytherapy in localized lipolysis: a clinical and radiological study
by: Azza G.A Farag, et al.
Published: (2019)