AutoPepVax, a Novel Machine-Learning-Based Program for Vaccine Design: Application to a Pan-Cancer Vaccine Targeting EGFR Missense Mutations

• Main Authors: Enrico Bautista (Author), Young Hyun Jung (Author), Manuela Jaramillo (Author), Harrish Ganesh (Author), Aryaan Varma (Author), Kush Savsani (Author), Sivanesan Dakshanamurthy (Author)
• Format: Book
• Published: MDPI AG, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The current epitope selection methods for peptide vaccines often rely on epitope binding affinity predictions, prompting the need for the development of more sophisticated in silico methods to determine immunologically relevant epitopes. Here, we developed AutoPepVax to expedite and improve the in s...