Unraveling enhanced brain delivery of paliperidone-loaded lipid nanoconstructs: pharmacokinetic, behavioral, biochemical, and histological aspects

• Main Authors: Saleha Rehman (Author), Bushra Nabi (Author), Amaan Javed (Author), Tahira Khan (Author), Ashif Iqubal (Author), Mohammad Javed Ansari (Author), Sanjula Baboota (Author), Javed Ali (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Antipsychotics are accompanied by extrapyramidal side effects that deter treatment adherence and patient compliance. Paliperidone (PPD), an atypical (second-generation) antipsychotic recommended for managing schizophrenia presents biopharmaceutical challenges and pharmacological constraints which di...