Cover Image

Selective CDK7 inhibition with BS-181 suppresses cell proliferation and induces cell cycle arrest and apoptosis in gastric cancer

Bo-Yong Wang, Quan-Yan Liu, Jun Cao, Ji-Wei Chen, Zhi-Su Liu Department of General Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, People’s Republic of China Abstract: Cyclin-dependent kinase (CDK) family members have been considered as attractive therapeutic targets for canc...

Full description

Saved in:

Bibliographic Details
Main Authors:	Wang BY (Author), Liu QY (Author), Cao J (Author), Chen JW (Author), Liu ZS (Author)
Format:	Book
Published:	Dove Medical Press, 2016-03-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Semisynthetic aurones A14 protects against T-cell acute lymphoblastic leukemia via suppressing proliferation and inducing cell cycle arrest with apoptosis
by: Meng Wang, et al.
Published: (2022)

Mitochondrion-Targeted NIR Therapeutic Agent Suppresses Melanoma by Inducing Apoptosis and Cell Cycle Arrest via E2F/Cyclin/CDK Pathway
by: Changzhen Sun, et al.
Published: (2022)

Effect of crude ethanolic seed extract from Mucuna pruriens on proliferation, apoptosis, and cell cycle arrest in gastric adenocarcinoma (AGS) cells
by: Arulvasu Chinnasamy, et al.
Published: (2024)

Regorafenib Suppresses Migration of and Induces Cell Cycle Arrest and Apoptosis in MCF-7 Cells
by: Dawei Wang, et al.
Published: (2021)

ARV-771 Acts as an Inducer of Cell Cycle Arrest and Apoptosis to Suppress Hepatocellular Carcinoma Progression
by: Yuanfei Deng, et al.
Published: (2022)

Rumex dentatus Inhibits Cell Proliferation, Arrests Cell Cycle, and Induces Apoptosis in MDA-MB-231 Cells through Suppression of the NF-κB Pathway
by: Riffat Batool, et al.
Published: (2017)

Jaceosidin inhibits proliferation of human bladder cancer T24 cells through induction of cell cycle arrest and apoptosis
by: Yong Li, et al.
Published: (2013)

Casticin treatment inhibits squamous cell carcinoma cell proliferation and arrests cell cycle in S phase
by: Yong-Bin Song, et al.
Published: (2016)

Adapalene Inhibits Prostate Cancer Cell Proliferation In Vitro and In Vivo by Inducing DNA Damage, S-phase Cell Cycle Arrest, and Apoptosis
by: Hai-bin Nong, et al.
Published: (2022)

Genetically engineered drug rhCNB induces apoptosis and cell cycle arrest in both gastric cancer cells and hepatoma cells
by: Guo Y, et al.
Published: (2018)

IDF-11774 Induces Cell Cycle Arrest and Apoptosis by Inhibiting HIF-1α in Gastric Cancer
by: Won-Ho Kim, et al.
Published: (2023)

Physalis pubescens L. branch and leaf extracts inhibit lymphoma proliferation by inducing apoptosis and cell cycle arrest
by: Li Yuan-Ce, et al.
Published: (2023)

Brevilin A Induces Cell Cycle Arrest and Apoptosis in Nasopharyngeal Carcinoma
by: Rui Liu, et al.
Published: (2019)

Germacrone exerts anti-cancer effects on gastric cancer through induction of cell cycle arrest and promotion of apoptosis
by: Lei Wu, et al.
Published: (2020)

The aberrant upstream pathway regulations of CDK1 protein were implicated in the proliferation and apoptosis of ovarian cancer cells
by: Ruitao Zhang, et al.
Published: (2017)

Nigella sativa plant extract inhibits the proliferation of MDA-MB-231 breast cancer cells via apoptosis and cell cycle arrest
by: Jie Ma, et al.
Published: (2024)

Isoalantolactone Induces Cell Cycle Arrest, Apoptosis and Autophagy in Colorectal Cancer Cells
by: Junkui Li, et al.
Published: (2022)

Novel [(N-alkyl-3-indolylmethylene)hydrazono]oxindoles arrest cell cycle and induce cell apoptosis by inhibiting CDK2 and Bcl-2: synthesis, biological evaluation and in silico studies
by: Tarfah Al-Warhi, et al.
Published: (2020)

Sensitization of gastric cancer cells to alkylating agents by glaucocalyxin B via cell cycle arrest and enhanced cell death
by: Ur Rahman MS, et al.
Published: (2017)

Theabrownin Induces Cell Apoptosis and Cell Cycle Arrest of Oligodendroglioma and Astrocytoma in Different Pathways
by: J. Y. Fu, et al.
Published: (2021)

Metformin inhibits cell proliferation in SKM-1 cells via AMPK-mediated cell cycle arrest
by: Xiaojia Zhou, et al.
Published: (2019)

Glucocappasalin Induces G2/M-Phase Arrest, Apoptosis, and Autophagy Pathways by Targeting CDK1 and PLK1 in Cervical Carcinoma Cells
by: Guangya Xu, et al.
Published: (2021)

Primula vulgaris extract induces cell cycle arrest and apoptosis in human cervix cancer cells
by: Selim Demir, et al.
Published: (2018)

A PLK1 inhibitor, RO3280, suppresses proliferation of SNU-16 gastric cancer cells via apoptosis
by: Fatih Yulak, et al.
Published: (2024)

Jianpi Yangwei decoction promotes apoptosis and suppresses proliferation of 5-fluorouracil resistant gastric cancer cells in vitro and in vivo
by: Huijuan Tang, et al.
Published: (2020)

Oxyresveratrol in Breast Cancer Cells: Synergistic Effect with Chemotherapeutics Doxorubicin or Melphalan on Proliferation, Cell Cycle Arrest, and Cell Death
by: Carlos Luan Alves Passos, et al.
Published: (2024)

Cytotoxic activities and effects of atractylodin and β-eudesmol on the cell cycle arrest and apoptosis on cholangiocarcinoma cell line
by: Kanawut Kotawong, et al.
Published: (2018)

Synadenium umbellatum Pax. promotes cell cycle arrest and induces apoptosis in K-562 leukemia cells
by: Mariana Flavia da Mota, et al.
Published: (2012)

<i>Micromeria fruticosa</i> Induces Cell Cycle Arrest and Apoptosis in Breast and Colorectal Cancer Cells
by: Waseem El-Huneidi, et al.
Published: (2020)

Nudol, a phenanthrene derivative from Dendrobium nobile, induces cell cycle arrest and apoptosis and inhibits migration in osteosarcoma cells
by: Zhang Y, et al.
Published: (2019)

MiR-663a Stimulates Proliferation and Suppresses Early Apoptosis of Human Spermatogonial Stem Cells by Targeting NFIX and Regulating Cell Cycle
by: Fan Zhou, et al.
Published: (2018)

Cell cycle arrest and apoptosis induction by methanolic leaves extracts of four Annonaceae plants
by: Kitti Pumiputavon, et al.
Published: (2017)

Ursolic Acid Regulates Cell Cycle and Proliferation in Colon Adenocarcinoma by Suppressing Cyclin B1
by: Minhui Yang, et al.
Published: (2021)

Phosphorylation of islet-1 serine 269 by CDK1 increases its transcriptional activity and promotes cell proliferation in gastric cancer
by: Qiong Shi, et al.
Published: (2021)

Effects of 8-Amino-Isocorydine, a Derivative of Isocorydine, on Gastric Carcinoma Cell Proliferation and Apoptosis
by: Lei Song, PhD, et al.
Published: (2021)

Cell Cycle Arrest and Apoptosis Induction by a New 2,4-Dinitrobenzenesulfonamide Derivative In Acute Leukemia Cells
by: Patricia Alves Almeida, et al.
Published: (2021)

Changes in the transcriptional activity of cell cycle regulator CDK1 and cell proliferation ki67 genes in invasive and non-invasive pancreatic ductal adenocarcinoma
by: A. V. Evseyev, et al.
Published: (2016)

Lucialdehyde B suppresses proliferation and induces mitochondria-dependent apoptosis in nasopharyngeal carcinoma CNE2 cells
by: Lingxue Liu, et al.
Published: (2023)

Hinokiflavone induces apoptosis, cell cycle arrest and autophagy in chronic myeloid leukemia cells through MAPK/NF-κB signaling pathway
by: Xiang Qin, et al.
Published: (2022)

Cucurbitacin B inhibits proliferation, induces G2/M cycle arrest and autophagy without affecting apoptosis but enhances MTT reduction in PC12 cells
by: Chuanhong Wu, et al.
Published: (2015)