Centenarians Alleviate Inflammaging by Changing the Ratio and Secretory Phenotypes of T Helper 17 and Regulatory T Cells

• Hlavní autoři: Lixing Zhou (Autor), Meiling Ge (Autor), Yan Zhang (Autor), Xiaochu Wu (Autor), Mi Leng (Autor), Chunmei Gan (Autor), Yi Mou (Autor), Jiao Zhou (Autor), C Alexander Valencia (Autor), Qiukui Hao (Autor), Bin Zhu (Autor), Biao Dong (Autor), Birong Dong (Autor)
• Médium: Kniha
• Vydáno: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

The immune system of centenarians remains active and young to prevent cancer and infections. Aging is associated with inflammaging, a persistent low-grade inflammatory state in which CD4+ T cells play a role. However, there are few studies that have been done on the CD4+ T cell subsets in centenaria...