m6A Modification-Association with Oxidative Stress and Implications on Eye Diseases

Oxidative stress (OS) refers to a state of imbalance between oxidation and antioxidation. OS is considered to be an important factor leading to aging and a range of diseases. The eyes are highly oxygen-consuming organs. Due to its continuous exposure to ultraviolet light, the eye is particularly vul...

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Main Authors: Yueqi Ni (Author), Hong Zhang (Author), Liang Chu (Author), Yin Zhao (Author)
Format: Book
Published: MDPI AG, 2023-02-01T00:00:00Z.
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001 doaj_fbcc5f9ce73e4eed9c1d82f6833e27d5
042 |a dc 
100 1 0 |a Yueqi Ni  |e author 
700 1 0 |a Hong Zhang  |e author 
700 1 0 |a Liang Chu  |e author 
700 1 0 |a Yin Zhao  |e author 
245 0 0 |a m6A Modification-Association with Oxidative Stress and Implications on Eye Diseases 
260 |b MDPI AG,   |c 2023-02-01T00:00:00Z. 
500 |a 10.3390/antiox12020510 
500 |a 2076-3921 
520 |a Oxidative stress (OS) refers to a state of imbalance between oxidation and antioxidation. OS is considered to be an important factor leading to aging and a range of diseases. The eyes are highly oxygen-consuming organs. Due to its continuous exposure to ultraviolet light, the eye is particularly vulnerable to the impact of OS, leading to eye diseases such as corneal disease, cataracts, glaucoma, etc. The N6-methyladenosine (m6A) modification is the most investigated RNA post-transcriptional modification and participates in a variety of cellular biological processes. In this study, we review the role of m6A modification in oxidative stress-induced eye diseases and some therapeutic methods to provide a relatively overall understanding of m6A modification in oxidative stress-related eye diseases. 
546 |a EN 
690 |a oxidative stress 
690 |a m6A modification 
690 |a eye diseases 
690 |a treatment 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Antioxidants, Vol 12, Iss 2, p 510 (2023) 
787 0 |n https://www.mdpi.com/2076-3921/12/2/510 
787 0 |n https://doaj.org/toc/2076-3921 
856 4 1 |u https://doaj.org/article/fbcc5f9ce73e4eed9c1d82f6833e27d5  |z Connect to this object online.