Systemic follicular lymphoma mimicking typical histological pattern of mycosis fungoides

Follicular lymphoma (FL) is typically presented in the form of lymphadenopathy, hepatosplenomegaly, and bone marrow infiltration. Herein, we report a case of systemic FL first presenting with a generalized asymptomatic rash with histological features of a superficial band-like lymphoid infiltrate an...

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Bibliographic Details
Main Authors: Yi-Wen Kuo (Author), Pei-Ying Hsieh (Author), Cheng-Hsiang Hsiao (Author), Po-Hsuan Lu (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2016-12-01T00:00:00Z.
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Summary:Follicular lymphoma (FL) is typically presented in the form of lymphadenopathy, hepatosplenomegaly, and bone marrow infiltration. Herein, we report a case of systemic FL first presenting with a generalized asymptomatic rash with histological features of a superficial band-like lymphoid infiltrate and areas of epidermotropism. Immunohistological studies revealed a B-cell lineage of the atypical lymphocytes. FL was diagnosed through a flow cytometric analysis of the bone marrow aspirate. As per our literature review, this is the first reported case of a systemic FL with secondary cutaneous involvement mimicking the stereotypical histological pattern of mycosis fungoides.
Item Description:1027-8117
10.1016/j.dsi.2016.03.003