FGF21 does not require adipocyte AMP-activated protein kinase (AMPK) or the phosphorylation of acetyl-CoA carboxylase (ACC) to mediate improvements in whole-body glucose homeostasis
Objective: Fibroblast growth factor 21 (FGF21) shows great potential for the treatment of obesity and type 2 diabetes, as its long-acting analogue reduces body weight and improves lipid profiles of participants in clinical studies; however, the intracellular mechanisms mediating these effects are po...
Saved in:
Main Authors: | Emilio P. Mottillo (Author), Eric M. Desjardins (Author), Andreas M. Fritzen (Author), Vito Z. Zou (Author), Justin D. Crane (Author), Julian M. Yabut (Author), Bente Kiens (Author), Derek M. Erion (Author), Adhiraj Lanba (Author), James G. Granneman (Author), Saswata Talukdar (Author), Gregory R. Steinberg (Author) |
---|---|
Format: | Book |
Published: |
Elsevier,
2017-06-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Targeting acetyl-CoA carboxylase 1 for cancer therapy
by: Yong Yu, et al.
Published: (2023) -
Sequences of acetyl CoA carboxylase promoter for tumour necrosis factor action
by: Keerang Park, et al.
Published: (1993) -
Synthesis and biological evaluation of 4-phenoxy-phenyl isoxazoles as novel acetyl-CoA carboxylase inhibitors
by: Xin Wu, et al.
Published: (2021) -
In silico identification of potential inhibitors of acyl carrier protein reductase and acetyl CoA carboxylase of Plasmodium falciparum in antimalarial therapy
by: Elliasu Y. Salifu, et al.
Published: (2023) -
FGF19 and FGF21: In NASH we trust
by: Saswata Talukdar, et al.
Published: (2021)