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Enhanced Bioavailability of AC1497, a Novel Anticancer Drug Candidate, via a Self-Nanoemulsifying Drug Delivery System

AC1497 is an effective dual inhibitor of malate dehydrogenase 1 and 2 targeting cancer metabolism. However, its poor aqueous solubility results in low bioavailability, limiting its clinical development. This study was conducted to develop an effective self-nanoemulsifying drug delivery system (SNEDD...

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Main Authors:	Kshitis Chandra Baral (Author), Jae-Geun Song (Author), Sang Hoon Lee (Author), Rajiv Bajracharya (Author), Godesi Sreenivasulu (Author), Minkyoung Kim (Author), Kyeong Lee (Author), Hyo-Kyung Han (Author)
Format:	Book
Published:	MDPI AG, 2021-07-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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