Helicobacter pylori eradication induce platelet recovery in idiopathic thrombocytopenic purpura

Recent reports have suggested an association between Helicobacter pylori infection and idiopathic thrombocytopenic purpura (1TP). The prevalence of H pylori infection and the effect of its eradication in a series of 30 ITP patients were investigated. H pylori infection has been documented in 13 pati...

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Main Authors: G. Emilia (Author), G. Longo (Author), M. Luppi (Author), G. Gandini (Author), M. Morselli (Author), L. Ferrara (Author), S. Amarri (Author), K. Cagossi (Author), G. Torelli (Author)
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Published: PAGEPress Publications, 2001-12-01T00:00:00Z.
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042 |a dc 
100 1 0 |a G. Emilia  |e author 
700 1 0 |a G. Longo  |e author 
700 1 0 |a M. Luppi  |e author 
700 1 0 |a G. Gandini  |e author 
700 1 0 |a M. Morselli  |e author 
700 1 0 |a L. Ferrara  |e author 
700 1 0 |a S. Amarri  |e author 
700 1 0 |a K. Cagossi  |e author 
700 1 0 |a G. Torelli  |e author 
245 0 0 |a Helicobacter pylori eradication induce platelet recovery in idiopathic thrombocytopenic purpura 
260 |b PAGEPress Publications,   |c 2001-12-01T00:00:00Z. 
500 |a 10.4081/reumatismo.2001.330 
500 |a 0048-7449 
500 |a 2240-2683 
520 |a Recent reports have suggested an association between Helicobacter pylori infection and idiopathic thrombocytopenic purpura (1TP). The prevalence of H pylori infection and the effect of its eradication in a series of 30 ITP patients were investigated. H pylori infection has been documented in 13 patients (43.33%) by 13C urea breath test and confirmed by histologic examination. Bacterium eradication with antibiotics, obtained in 12 of 13 infected patients (92.3%), led to a complete response in 4 (33.33%) and to a partial response (platelets 90 x IO^L-120 x IO'VL) in 2 (16.66%). The response was maintained for a median of 8.33 months, but 1 patient relapsed 7 months after eradication. Search for H pylori infection seems appropriate in ITP patients at diagnosis. Bacterium eradication provides a new good option for a non immunosuppressive treatment in some ITP patients. (Blood 2001; 97: 812-814) 
546 |a EN 
546 |a IT 
690 |a Medicine 
690 |a R 
690 |a Internal medicine 
690 |a RC31-1245 
655 7 |a article  |2 local 
786 0 |n Reumatismo, Vol 53, Iss 4 (2001) 
787 0 |n https://reumatismo.org/index.php/reuma/article/view/49 
787 0 |n https://doaj.org/toc/0048-7449 
787 0 |n https://doaj.org/toc/2240-2683 
856 4 1 |u https://doaj.org/article/fc65a2bfa5d245b195d259ebdf71a2c8  |z Connect to this object online.