Novel Etiological and Therapeutic Strategies for Neurodiseases: Epigenetic Understanding of Gene-Environment Interactions

• Main Authors: Takeo Kubota (Author), Kunio Miyake (Author), Takae Hirasawa (Author), Kaoru Nagai (Author), Tsuyoshi Koide (Author)
• Format: Book
• Published: Elsevier, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Epigenetics is a mechanism that regulates gene expression not depending on the underlying DNA sequence, but on the chemical modifications of DNA and histone proteins. Defects in the factors involved in epigenetic regulation cause congenital neurodevelopmental diseases, and thus, epigenetic regulatio...