Autoimmune Polyglandular Syndrome Type 1: a case report

• Main Authors: Sayed Mahmoud Sajjadi-Jazi (Author), Akbar Soltani (Author), Samaneh Enayati (Author), Armita Kakavand Hamidi (Author), Mahsa M. Amoli (Author)
• Format: Book
• Published: BMC, 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Mutations of the autoimmune regulator gene (AIRE), located on chromosome 21q22.3, are recognized as the cause of a rare monogenic organ-specific autoimmune disorder called autoimmune polyglandular syndrome type 1 (APS-1). Three major components of this syndrome include chronic mu...