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Limited Sampling Modeling for Estimation of Phenotypic Metrics for CYP Enzymes and the ABCB1 Transporter Using a Cocktail Approach

Plasma concentration data points (n = 2,640) from 16 healthy adults were used to develop and validate limited sampling strategies (LSS) for estimation of phenotypic metrics for CYP enzymes and the ABCB1 transporter, using a cocktail of subtherapeutic doses of the selective probes caffeine (CYP1A2),...

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Main Authors:	Eduardo Barbosa Coelho (Author), Diego Alberto Ciscato Cusinato (Author), João Paulo Ximenez (Author), Vera Lucia Lanchote (Author), Claudio José Struchiner (Author), Guilherme Suarez-Kurtz (Author)
Format:	Book
Published:	Frontiers Media S.A., 2020-02-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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