Cellulitis with Leukocytopenia as an Initial Sign of Acute Promyelocytic Leukemia
Patients with hematologic malignancies are immunosuppressive and may develop cutaneous or invasive infections as a primary sign of immune suppression. Acute promyelocytic leukemia (acute myeloid leukemia M3) is caused by translocation of reciprocal chromosomal rearrangement t(15;17), which produces...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
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Karger Publishers,
2012-03-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | Patients with hematologic malignancies are immunosuppressive and may develop cutaneous or invasive infections as a primary sign of immune suppression. Acute promyelocytic leukemia (acute myeloid leukemia M3) is caused by translocation of reciprocal chromosomal rearrangement t(15;17), which produces an oncogenic protein. We herein describe a 71-year-old man having cellulitis with leukocytopenia as a first sign of acute promyelocytic leukemia. Dermatologists and hematologists should keep in mind that patients with a hematologic malignancy, such as acute promyelocytic leukemia, can develop cellulitis with leukocytopenia. |
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| Item Description: | 1662-6567 10.1159/000337195 |