Virology features of a family cluster of SARS-CoV-2 infections in Shanghai, China

The global spread of SARS-CoV-2 is currently continuing, and the World Health Organization has announced the risk assessment of the viruses as high. In this study, we analyzed virology features of SARS-CoV-2 causing a family cluster outbreak. Among the six family members, five have been laboratory-c...

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Bibliographic Details
Main Authors: Yanqiu Zhou (Author), Zheng Teng (Author), Hongyou Chen (Author), Xiaoxian Cui (Author), Fanghao Fang (Author), Jiabin Mou (Author), Hui Jiang (Author), Xi Zhang (Author)
Format: Book
Published: Elsevier, 2021-08-01T00:00:00Z.
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Summary:The global spread of SARS-CoV-2 is currently continuing, and the World Health Organization has announced the risk assessment of the viruses as high. In this study, we analyzed virology features of SARS-CoV-2 causing a family cluster outbreak. Among the six family members, five have been laboratory-confirmed infection of SARS-CoV-2 viruses. A total of five SARS-CoV-2 viruses have been isolated from the nasopharyngeal swabs. The complete genome of the viruses exhibited 100% nucleotide identity with each other. Only two nucleotide differences have been observed between genomes of the isolated viruses and the HCoV/Wuhan/ IVDC-HB-01/2019 strain. Therefore, SARS-CoV-2 has been confirmed as the causation of the family cluster infections.
Item Description:2590-0536
10.1016/j.bsheal.2021.05.003