Risk of hepatotoxicity with trastuzumab emtansine in breast cancer patients: a systematic review and meta-analysis

• Main Authors: Amani M. Cobert (Author), Catherine Helms (Author), Chris Larck (Author), Donald C. Moore (Author)
• פורמט: ספר
• יצא לאור: SAGE Publishing, 2020-04-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Background: Trastuzumab emtansine (T-DM1) is an anti-HER2 antibody-drug conjugate indicated for the treatment of HER2-positive breast cancer. One of the most severe adverse events reported with T-DM1 is hepatotoxicity. The objective of our meta-analysis is to investigate the risk of hepatic adverse...