Characterization of NF-kB-mediated inhibition of catechol-<it>O</it>-methyltransferase

• Main Authors: Conrad Matthew (Author), Wentworth Sean (Author), Qian Li (Author), Nackley Andrea G (Author), Tchivileva Inna E (Author), Diatchenko Luda B (Author)
• Formato: Livro
• Publicado em: SAGE Publishing, 2009-03-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Catechol-<it>O</it>-methyltransferase (COMT), an enzyme that metabolizes catecholamines, has recently been implicated in the modulation of pain. Specifically, low COMT activity is associated with heightened pain perceptio...