Optimizing dose-schedule regimens with bayesian adaptive designs: opportunities and challenges
Due to the small sample sizes in early-phase clinical trials, the toxicity and efficacy profiles of the dose-schedule regimens determined for subsequent trials may not be well established. The recent development of novel anti-tumor treatments and combination therapies further complicates the problem...
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Main Authors: | Xin Chen (Author), Ruyue He (Author), Xinyi Chen (Author), Liyun Jiang (Author), Fei Wang (Author) |
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Format: | Book |
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Frontiers Media S.A.,
2023-11-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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