Optimizing dose-schedule regimens with bayesian adaptive designs: opportunities and challenges

Due to the small sample sizes in early-phase clinical trials, the toxicity and efficacy profiles of the dose-schedule regimens determined for subsequent trials may not be well established. The recent development of novel anti-tumor treatments and combination therapies further complicates the problem...

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Bibliographic Details
Main Authors: Xin Chen (Author), Ruyue He (Author), Xinyi Chen (Author), Liyun Jiang (Author), Fei Wang (Author)
Format: Book
Published: Frontiers Media S.A., 2023-11-01T00:00:00Z.
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