Nanodevices for the Efficient Codelivery of CRISPR-Cas9 Editing Machinery and an Entrapped Cargo: A Proposal for Dual Anti-Inflammatory Therapy

• Main Authors: Alba García-Fernández (Author), Gema Vivo-Llorca (Author), Mónica Sancho (Author), Alicia Belén García-Jareño (Author), Laura Ramírez-Jiménez (Author), Eloísa Barber-Cano (Author), José Ramón Murguía (Author), Mar Orzáez (Author), Félix Sancenón (Author), Ramón Martínez-Máñez (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this article, we report one of the few examples of nanoparticles capable of simultaneously delivering CRISPR-Cas9 gene-editing machinery and releasing drugs for one-shot treatments. Considering the complexity of inflammation in diseases, the synergistic effect of nanoparticles for gene-editing/dr...