Secukinumab-induced Raynaud's phenomenon: first report in the literature

Secukinumab is an IL-17A antagonist that has proven efficacy in the treatment of patients with ankylosing spondylitis (AS) and psoriatic arthritis. Side effects of the drug include infections, skin rashes, and allergic reactions. Raynaud's phenomenon (RP), a vasospastic syndrome and an importan...

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Main Author: Senol Kobak (Author)
Format: Book
Published: SAGE Publishing, 2020-02-01T00:00:00Z.
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100 1 0 |a Senol Kobak  |e author 
245 0 0 |a Secukinumab-induced Raynaud's phenomenon: first report in the literature 
260 |b SAGE Publishing,   |c 2020-02-01T00:00:00Z. 
500 |a 2042-0994 
500 |a 10.1177/2042098620905976 
520 |a Secukinumab is an IL-17A antagonist that has proven efficacy in the treatment of patients with ankylosing spondylitis (AS) and psoriatic arthritis. Side effects of the drug include infections, skin rashes, and allergic reactions. Raynaud's phenomenon (RP), a vasospastic syndrome and an important feature of different connective tissue diseases, is not an expected finding in AS patients. This article reports the development of secukinumab-related RP in a 35-year-old female patient with AS. Treatment with secukinumab was continued and RP was treated with low-dose aspirin and a calcium-channel blocker. 
546 |a EN 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Therapeutic Advances in Drug Safety, Vol 11 (2020) 
787 0 |n https://doi.org/10.1177/2042098620905976 
787 0 |n https://doaj.org/toc/2042-0994 
856 4 1 |u https://doaj.org/article/fe182a8236044f83a96dfe6e9211b63d  |z Connect to this object online.