Hot-Melt Extrusion-Based Dexamethasone-PLGA Implants: Physicochemical, Physicomechanical, and Surface Morphological Properties and In Vitro Release Corrected for Drug Degradation

Developing bioequivalent (BE) generic products of complex dosage forms like intravitreal implants (IVIs) of corticosteroids such as dexamethasone prepared using hot-melt extrusion (HME), based on biodegradable poly (lactide-co-glycolide) (PLGA) polymers, can be challenging. A better understanding of...

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Bibliographic Details
Main Authors: Alireza (Allen) (Author), Brock A. Matter (Author), Rachel R. Hartman (Author), David W. A. Bourne (Author), Yan Wang (Author), Stephanie Choi (Author), Uday B. Kompella (Author)
Format: Book
Published: MDPI AG, 2024-07-01T00:00:00Z.
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