Hot-Melt Extrusion-Based Dexamethasone-PLGA Implants: Physicochemical, Physicomechanical, and Surface Morphological Properties and In Vitro Release Corrected for Drug Degradation
Developing bioequivalent (BE) generic products of complex dosage forms like intravitreal implants (IVIs) of corticosteroids such as dexamethasone prepared using hot-melt extrusion (HME), based on biodegradable poly (lactide-co-glycolide) (PLGA) polymers, can be challenging. A better understanding of...
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Main Authors: | Alireza (Allen) (Author), Brock A. Matter (Author), Rachel R. Hartman (Author), David W. A. Bourne (Author), Yan Wang (Author), Stephanie Choi (Author), Uday B. Kompella (Author) |
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Format: | Book |
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MDPI AG,
2024-07-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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