American tegumentary leishmaniasis - a case of therapeutic challenge

• Những tác giả chính: Daíne Vargas Couto (Tác giả), Gunter Hans Filho (Tác giả), Marcelo Zanolli Medeiros (Tác giả), Carolina Faria Santos Vicari (Tác giả), Aline Blanco Barbosa (Tác giả), Luiz Carlos Takita (Tác giả)
• Định dạng: Sách
• Được phát hành: Sociedade Brasileira de Dermatologia, 2014-12-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.
• Notes: 0365-0596; 10.1590/abd1806-4841.20143073
• Keywords: Leishmania guyanensis; Leishmaniasis, cutaneous; Pentamidine; Skin diseases, parasitic; Dermatology; RL1-803
• Source: Anais Brasileiros de Dermatologia, Vol 89, Iss 6, Pp 974-976 (2014)

American Tegumentary Leishmaniasis (ATL) is a chronic, non-contagious, infectious disease affecting millions of people worldwide. The timely and proper treatment is of great importance to prevent the disease from progressing to destructive and severe forms. Treatment for ATL recommended by the Brazilian Ministry of Health is similar for the whole country, regardless of the species of Leishmania. It is known that the response to treatment may vary with the strain of the parasite, the immune status of the patient and clinical form. We report the case of a healthy patient, coming from Manaus, Amazonas state, Brazil, who presented resistance to treatment with N-methyl-glutamine and liposomal amphotericin B, only being healed after using pentamidine.