Intravesical Oxybutynin for Urgent Bladder Rescue in a Newborn with Posterior Urethral Valves

Posterior urethral valves are the most common cause of bladder outlet obstruction in male newborns. Initial catheter drainage alleviates the urethral obstruction before definitive management by valve ablation. Newborns with posterior urethral valves often present with hypercontractile bladders that...

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Main Authors: Ada Molina Caballero (Author), Alberto Pérez Martínez (Author), Concepción Goñi Orayen (Author), Gemma Sierra Colomina (Author), Ana Lavilla Oiz (Author), Yolanda Armendariz Cuevas (Author)
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Published: Georg Thieme Verlag KG, 2019-01-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Ada Molina Caballero  |e author 
700 1 0 |a Alberto Pérez Martínez  |e author 
700 1 0 |a Concepción Goñi Orayen  |e author 
700 1 0 |a Gemma Sierra Colomina  |e author 
700 1 0 |a Ana Lavilla Oiz  |e author 
700 1 0 |a Yolanda Armendariz Cuevas  |e author 
245 0 0 |a Intravesical Oxybutynin for Urgent Bladder Rescue in a Newborn with Posterior Urethral Valves 
260 |b Georg Thieme Verlag KG,   |c 2019-01-01T00:00:00Z. 
500 |a 2194-7619 
500 |a 2194-7627 
500 |a 10.1055/s-0039-3399565 
520 |a Posterior urethral valves are the most common cause of bladder outlet obstruction in male newborns. Initial catheter drainage alleviates the urethral obstruction before definitive management by valve ablation. Newborns with posterior urethral valves often present with hypercontractile bladders that may inhibit upper tract drainage despite bladder catheterization. Anticholinergic agents are commonly used to treat detrusor hyperactivity, with oxybutynin being the most commonly used. We report the first case of a newborn with posterior urethral valves and ureterovesical junction obstruction caused by detrusor hypertrophy who underwent urgent intravesical instillation of oxybutynin at high doses in an attempt to avoid a diversion procedure. 
546 |a EN 
690 |a posterior urethral valves 
690 |a detrusor hypertrophy 
690 |a oxybutynin 
690 |a intravesical 
690 |a Pediatrics 
690 |a RJ1-570 
690 |a Surgery 
690 |a RD1-811 
655 7 |a article  |2 local 
786 0 |n European Journal of Pediatric Surgery Reports, Vol 07, Iss 01, Pp e90-e92 (2019) 
787 0 |n http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-3399565 
787 0 |n https://doaj.org/toc/2194-7619 
787 0 |n https://doaj.org/toc/2194-7627 
856 4 1 |u https://doaj.org/article/fe3ad513bb5c4c01b2ae243d15b5c337  |z Connect to this object online.