Pharmacokinetics and Pharmacodynamics of diclofenac in the presence and absence of glibenclamide in the rat
PURPOSE. There are evidences that glibenclamide, a sulfonylurea antidiabetic agent, reduces the analgesic action of non-steroidal anti-inflammatory drugs (NSAIDs), opioids and neuromodulators in animal models. The purpose of this work was to examine in the rat if such interaction involves pharmacoki...
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| Main Authors: | , , |
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| Format: | Book |
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Frontiers Media S.A.,
2016-11-01T00:00:00Z.
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