Effects of naringenin on the pharmacokinetics of tofacitinib in rats

• Main Authors: Bo Wang (Author), Jiquan Shen (Author), Quan Zhou (Author), Deru Meng (Author), Youwu He (Author), Feifei Chen (Author), Shuanghu Wang (Author), Weiping Ji (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context Naringenin and tofacitinib are often used together for treatment of rheumatoid arthritis in Chinese clinics. Objective This experiment investigates the effect of naringenin on the pharmacokinetics of tofacitinib in rats. Materials and methods Twelve Sprague-Dawley rats were randomly divided...