Total Body Irradiation in Haematopoietic Stem Cell Transplantation for Paediatric Acute Lymphoblastic Leukaemia: Review of the Literature and Future Directions

• Main Authors: Bianca A. W. Hoeben (Author), Jeffrey Y. C. Wong (Author), Lotte S. Fog (Author), Christoph Losert (Author), Andrea R. Filippi (Author), Søren M. Bentzen (Author), Adriana Balduzzi (Author), Lena Specht (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Total body irradiation (TBI) has been a pivotal component of the conditioning regimen for allogeneic myeloablative haematopoietic stem cell transplantation (HSCT) in very-high-risk acute lymphoblastic leukaemia (ALL) for decades, especially in children and young adults. The myeloablative conditionin...