Unveiling the mechanisms of neuropathic pain suppression: perineural resiniferatoxin targets Trpv1 and beyond

• Váldodahkkit: Safa Shehab (Dahkki), Hayate Javed (Dahkki), Aishwarya Mary Johnson (Dahkki), Saeed Tariq (Dahkki), Challagandla Anil Kumar (Dahkki), Bright Starling Emerald (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2023-11-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Neuropathic pain arises from damage or disorders affecting the somatosensory system. In rats, L5 nerve injury induces thermal and mechanical hypersensitivity/hyperalgesia. Recently, we demonstrated that applying resiniferatoxin (RTX) directly on uninjured L3 and L4 nerves alleviated thermal and mech...