A Data-Driven Approach for Leveraging Inline and Offline Data to Determine the Causes of Monoclonal Antibody Productivity Reduction in the Commercial-Scale Cell Culture Process

• Principais autores: Sheng Zhang (Autor), Hang Chen (Autor), Yuxiang Wan (Autor), Haibin Wang (Autor), Haibin Qu (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2024-08-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The monoclonal antibody (mAb) manufacturing process comes with high profits and high costs, and thus mAb productivity is of vital importance. However, many factors can impact the cell culture process, and lead to mAb productivity reduction. Nowadays, the biopharma industry is actively employing manu...