Inflammatory bowel disease: an overview of Chinese herbal medicine formula-based treatment

Abstract Inflammatory bowel disease (IBD) is a chronic recurrent inflammatory disease of the intestine, including Crohn's disease (CD) and ulcerative colitis (UC), whose etiology and pathogenesis have not been fully understood. Due to its prolonged course and chronic recurrence, IBD imposes a h...

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Main Authors: Shuo Yuan (Author), Qi Wang (Author), Jiao Li (Author), Jia-Chen Xue (Author), You Li (Author), Huan Meng (Author), Xiao-Ting Hou (Author), Ji-Xing Nan (Author), Qing-Gao Zhang (Author)
Format: Book
Published: BMC, 2022-06-01T00:00:00Z.
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001 doaj_fea7f53133394d33b767cf2fce8e355c
042 |a dc 
100 1 0 |a Shuo Yuan  |e author 
700 1 0 |a Qi Wang  |e author 
700 1 0 |a Jiao Li  |e author 
700 1 0 |a Jia-Chen Xue  |e author 
700 1 0 |a You Li  |e author 
700 1 0 |a Huan Meng  |e author 
700 1 0 |a Xiao-Ting Hou  |e author 
700 1 0 |a Ji-Xing Nan  |e author 
700 1 0 |a Qing-Gao Zhang  |e author 
245 0 0 |a Inflammatory bowel disease: an overview of Chinese herbal medicine formula-based treatment 
260 |b BMC,   |c 2022-06-01T00:00:00Z. 
500 |a 10.1186/s13020-022-00633-4 
500 |a 1749-8546 
520 |a Abstract Inflammatory bowel disease (IBD) is a chronic recurrent inflammatory disease of the intestine, including Crohn's disease (CD) and ulcerative colitis (UC), whose etiology and pathogenesis have not been fully understood. Due to its prolonged course and chronic recurrence, IBD imposes a heavy economic burden and psychological stress on patients. Traditional Chinese Herbal Medicine has unique advantages in IBD treatment because of its symptomatic treatment. However, the advantages of the Chinese Herbal Medicine Formula (CHMF) have rarely been discussed. In recent years, many scholars have conducted fundamental studies on CHMF to delay IBD from different perspectives and found that CHMF may help maintain intestinal integrity, reduce inflammation, and decrease oxidative stress, thus playing a positive role in the treatment of IBD. Therefore, this review focuses on the mechanisms associated with CHMF in IBD treatment. CHMF has apparent advantages. In addition to the exact composition and controlled quality of modern drugs, it also has multi-component and multi-target synergistic effects. CHMF has good prospects in the treatment of IBD, but its multi-agent composition and wide range of targets exacerbate the difficulty of studying its treatment of IBD. Future research on CHMF-related mechanisms is needed to achieve better efficacy. 
546 |a EN 
690 |a Autophagy 
690 |a Chinese herbal medicine formula 
690 |a Immunity 
690 |a Inflammatory bowel disease 
690 |a Intestinal mucosal barrier 
690 |a Oxidative stress 
690 |a Other systems of medicine 
690 |a RZ201-999 
655 7 |a article  |2 local 
786 0 |n Chinese Medicine, Vol 17, Iss 1, Pp 1-17 (2022) 
787 0 |n https://doi.org/10.1186/s13020-022-00633-4 
787 0 |n https://doaj.org/toc/1749-8546 
856 4 1 |u https://doaj.org/article/fea7f53133394d33b767cf2fce8e355c  |z Connect to this object online.