Fatal form of immune reconstitution inflammatory syndrome (IRIS) developed post pneumonia in a solid organ transplant recipient
Abstract Background Immune reconstitution inflammatory syndrome (IRIS) is a complex phenomenon commonly diagnosed with human immunodeficiency virus (HIV). However, rarely, IRIS can develop with other diseases outside of HIV. We are discussing a rare presentation of IRIS following a pseudomonal infec...
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| Main Authors: | , , , , , , |
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| Format: | Book |
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SpringerOpen,
2024-02-01T00:00:00Z.
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| Summary: | Abstract Background Immune reconstitution inflammatory syndrome (IRIS) is a complex phenomenon commonly diagnosed with human immunodeficiency virus (HIV). However, rarely, IRIS can develop with other diseases outside of HIV. We are discussing a rare presentation of IRIS following a pseudomonal infection. Case presentation We present a 79-year-old Hispanic male who completed a course of cefepime for Pseudomonas aeruginosa hospital-acquired pneumonia. The patient had a 21-year history of solid organ transplant and immunosuppressive therapy, and he developed a fatal form of IRIS post-Pseudomonas aeruginosa. Conclusions IRIS may occur in any immunocompromised patient who develops an insidious onset of unexplained clinical and serological deterioration. |
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| Item Description: | 10.1186/s43162-024-00286-9 2090-9098 |