Q-fever prosthetic valve endocarditis in a patient with SLE and antiphospholipid antibody syndrome

Q fever prosthetic valve endocarditis in association with antiphospholipid antibody syndrome (APS) in systemic lupus erythematosus (SLE) has not been previously reported. Here, we report a 22-year-old Saudi female diagnosed with SLE and APS. She had mitral valve replacement with bio-prosthesis five...

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Main Authors: Mayyadah H. Alabdely (Author), Noha Mukhtar (Author), Ahmad Alshaikh (Author), Magid Halim (Author), Shmayel Mohammed (Author), Claudio Pragliola (Author), Ali S. Omrani (Author)
Format: Book
Published: Elsevier, 2020-05-01T00:00:00Z.
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100 1 0 |a Mayyadah H. Alabdely  |e author 
700 1 0 |a Noha Mukhtar  |e author 
700 1 0 |a Ahmad Alshaikh  |e author 
700 1 0 |a Magid Halim  |e author 
700 1 0 |a Shmayel Mohammed  |e author 
700 1 0 |a Claudio Pragliola  |e author 
700 1 0 |a Ali S. Omrani  |e author 
245 0 0 |a Q-fever prosthetic valve endocarditis in a patient with SLE and antiphospholipid antibody syndrome 
260 |b Elsevier,   |c 2020-05-01T00:00:00Z. 
500 |a 1876-0341 
500 |a 10.1016/j.jiph.2020.02.036 
520 |a Q fever prosthetic valve endocarditis in association with antiphospholipid antibody syndrome (APS) in systemic lupus erythematosus (SLE) has not been previously reported. Here, we report a 22-year-old Saudi female diagnosed with SLE and APS. She had mitral valve replacement with bio-prosthesis five years earlier for Libman-Sack endocarditis. She presented with two months' history of fever, cough, palpitations, and progressive shortness of breath. A transthoracic echocardiogram showed a degenerative mitral valve prosthesis with a large mass causing severe obstruction. Open heart surgery revealed multiple masses on the mitral valve. PCR from the resected tissues was positive for Coxiella burnetii DNA. Q fever serology showed phase two IgG 1:2048, phase one IgG 1:512, and IgM 1:1024. The valve was replaced with a bio-prosthesis. She was well at 12 months of follow-up. Keywords: Q fever, Coxiella burnetii, SLE, Antiphospholipid, Endocarditis 
546 |a EN 
690 |a Infectious and parasitic diseases 
690 |a RC109-216 
690 |a Public aspects of medicine 
690 |a RA1-1270 
655 7 |a article  |2 local 
786 0 |n Journal of Infection and Public Health, Vol 13, Iss 5, Pp 821-823 (2020) 
787 0 |n http://www.sciencedirect.com/science/article/pii/S1876034120303889 
787 0 |n https://doaj.org/toc/1876-0341 
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