Structural and pharmacological insights into cordycepin for neoplasms and metabolic disorders

• Principais autores: Jinming Zhang (Autor), Ziling Yang (Autor), Zhuo Zhao (Autor), Nan Zhang (Autor)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2024-06-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Cytotoxic adenosine analogues were among the earliest chemotherapeutic agents utilised in cancer treatment. Cordycepin, a natural derivative of adenosine discovered in the fungus Ophiocordyceps sinensis, directly inhibits tumours not only by impeding biosynthesis, inducing apoptosis or autophagy, re...